Copenhagen, Hovedstaden, DK
Lundbeck’s passion links to our purpose about restoring brain health so every person can be their best. We strive to make a real difference to patients. By developing innovative treatments, we improve the lives of people living with brain diseases. Your dedication is crucial. That is why you can expect us to be committed to your progress, so you can stay committed to ours.
We are seeking a highly motivated individual with expert level knowledge of medicinal chemistry and first-in-human enabling CMC (Chemistry, Manufacturing and Controls) development of drug candidates that are based on synthesized drug modalities. As an outstanding medicinal chemist or CMC specialist with documented experience you can become an integral part of a world-class drug development organization that is tirelessly dedicated to restoring brain health.
As Scientific Lead in Early Stage CMC Development you will take a leading role in defining strategies and driving forward CMC development activities for new drug candidates advancing to GLP toxicology and Phase 1. You will work as part of a cross-functional team with experts in preformulation, solid form science, process chemistry, analytical development and formulation. To facilitate appropriate and streamlined development activities, you will liaise with Lundbeck’s Molecular Discovery and Innovation (medicinal chemistry research) organization and provide a CMC perspective.
Within Lundbeck the Chemical & Pharmaceutical Development (C&PD) organization is responsible for the CMC development and innovation progression of new drug candidates based on chemically synthesized molecules. This position will report into the Solid Form Science (SFS) department and maintain strong collaboration with the departments of process chemistry, pharmaceutical development and analytical development.
Your job and key responsibilities
The main responsibilities of the position are two-fold. First, collaborating with Lundbeck’s medicinal chemistry team and reviewing each project/development candidate(s) with a forward thinking focus on CMC challenges, risks and opportunities. Your ability to identify these challenges and communicate them in your interactions with Lundbeck’s medicinal chemistry team is of vital importance to facilitate the selection of drug candidates. Second, devising an optimal strategy for advancing the compounds into early development. This work will require close collaboration with experts in preformulation, solid state science, analytical development, formulation and process chemistry. You will be responsible for managing, tracking and summarizing the development activities and will be accountable to both SFS and senior C&PD leadership.
This is a unique and exciting opportunity to work in a highly collaborative area of early drug development with the ability to grow and develop your skill set in medicinal chemistry and early stage CMC development. This is a senior-level appointment; the specific level of appointment will depend on your level of experience.
Your workplace will be located at our Corporate Headquarters in Valby (Copenhagen area), Denmark. The position requires a limited amount of travelling.
Qualifications and competencies
- You have a PhD in a relevant area of science and have 10+ years’ experience in either medicinal chemistry or CMC specifically advancing early development projects into Phase 1 clinical study. You must have demonstratable experience of drug development in the pharmaceutical industry.
- You have a demonstratable track record of impacting on drug discovery and development projects.
- You promote and live a culture of open scientific debate and agile, accountable decision-making.
- You are an exceptional communicator, able to communicate scientific details and project development strategies to your collaborators in the CMC organization and to management at the right level.
- You have strong organizational and project management skills.
For further information, please contact Thomas Vetter, Director of Solid Form Science, on . Your application and CV should not be sent via email.
We also recommend that you visit our website .
Please click on the link below to apply for the job. Applications will be reviewed on an ongoing basis and must be received no later than 19th May 2021. Your application should include a cover letter stating your experience and motivation for the position, curriculum vitae, as well as the names and contact details for two references.
Lundbeck is a global pharmaceutical company specialized in brain diseases. For more than 70 years, we have been at the forefront of neuroscience research. We are tirelessly dedicated to restoring brain health, so every person can be their best.
Millions of people worldwide live with brain diseases, and far too many suffer due to inadequate treatment, discrimination, a reduced number of working days, early retirement, and other unnecessary consequences. Every day, we strive for improved treatment and a better life for people living with brain diseases – we call this Progress in Mind.
Our approximately 5,800 employees in more than 50 countries are engaged in the entire value chain throughout research, development, production, marketing, and sales. Our pipeline consists of several R&D programs, and our products are available in more than 100 countries. We have research centers in Denmark and the US, and our production facilities are located in Denmark, France, and Italy. Lundbeck generated revenue of DKK 17 billion in 2019 (EUR 2.3 billion; USD 2.6 billion).